Programmable nucleases for genome editing.

Programmable nucleases for genome editing.

Model of a pair of ZFNs bound to DNA.

Model of a pair of ZFNs bound to DNA.

Illustration of the consequences of targeted genome cleavage. After nuclease cleavage at a unique site (red lightning bolt), cells repair the break, sometimes inaccurately (NHEj), or by copying a template (HDR).

Illustration of the consequences of targeted genome cleavage. After nuclease cleavage at a unique site (red lightning bolt), cells repair the break, sometimes inaccurately (NHEj), or by copying a template (HDR).

 Genome Editing

Thank you for visiting the Carroll Lab website.

I am interested in the broader uses of genome editing and the societal implications of such uses. For example, this powerful technology offers many opportunities for improving food organisms, both crop plants and livestock. Medical applications of genome editing are in their infancy, but also have great promise. We want to ensure that such uses are developed safely and their benefits are distributed appropriately. Complex ethical and societal issues are raised by these prospects, particularly when modifications to the human germline are considered.

I closed my research lab on July 1, 2018, so there are no research opportunities available with me.

I am very grateful to all the people who have worked with me in my 45+ years at the University of Utah and who have contributed to the things we learned and technologies we developed.

I plan to remain on the faculty for several more years.